Manufacturing is experiencing a seismic shift from rigid, rule-based automation to truly autonomous, adaptive operations. While traditional digital transformation initiatives delivered greater visibility and deterministic control, they often fell short in enabling rapid, real-time decision-making during disruptions such as late deliveries or equipment breakdowns. Human intervention remains essential to interpret insights and drive action in the age of smart manufacturing.
Agentic artificial intelligence (AI) is fundamentally changing the game. As the next evolution of AI, agentic AI systems can act autonomously to achieve specific goals, moving beyond simply following preprogrammed instructions. These systems are transforming smart manufacturing from a data-rich to a decision-rich environment. Through goal-oriented reasoning, these systems function as “digital full-time equivalents” (FTEs), actively sensing, reasoning, negotiating, deciding and acting across interconnected manufacturing processes. Critically, these systems operate within stringent safety and quality parameters, with minimal need for human intervention.
Imagine a smart factory that doesn’t just react to problems, but anticipates failures, reroutes schedules, coordinates repairs and optimizes outputs, all done autonomously. This shift creates a self-healing and self-optimizing shop floor where intelligent agents collaborate to drive agility, efficiency and resilience.
As agentic AI transforms manufacturing, it’s important to distinguish it from traditional AI agents. AI agents are systems that sense and act to achieve specific tasks. They are task oriented and reactive, operating based on programmed logic or a machine learning model with limited autonomy. For example, a quality inspection AI agent uses computer vision to scan products on an assembly line and flags defects based on trained image recognition models. It performs a specific task (defect detection) and reacts to visual input but does not adapt its strategy or collaborate with other systems autonomously. Agentic AI, on the other hand, refers to advanced AI systems that exhibit higher degrees of autonomy, proactivity and adaptability. These systems can set subgoals, plan multistep actions, collaborate with other agents or humans, and learn from feedback to improve over time, rather than simply executing predefined tasks. Agentic AI systems operate as single agents or as networks of multiple agents. The difference between single-agent and multi-agent systems is defined below:
For operations spanning multiple ISA-95 standard levels and requiring real-time decisions to balance conflicting key performance indicators (KPIs), multiagent systems are becoming the clear choice.
AI agents can be strategically deployed to automate workflows, collect and disseminate information, and monitor operations across an entire plant. By orchestrating these agents, manufacturers can unlock new levels of efficiency, agility and quality.
While the possibilities with agentic AI are vast, manufacturing leaders must prioritize the right opportunities by evaluating them across two key dimensions:
Relevance for agentic AI, which may consider these three factors:
Business value
Building effective agentic AI solutions requires a structured approach that integrates use case selection, architecture design, technical execution, and governance throughout development and deployment.
As operational complexity increases, AI-driven solutions are essential for sustained growth and efficiency. We stand at the forefront of this transformation, offering proven tools and industry expertise to accelerate your agentic AI adoption.
Looking for a detailed plan to guide your strategic implementation with a focus on governance, cultural change, and long-term value?
Check out our recent article on enterprise transformation for a step-by-step strategic roadmap.
Special thanks to Kreeti Mahajan, Parag Gajjar, Sarvotham Shetty and Debashish Chatterjee for their coauthorship of this article.