Imagine a commercial landscape where AI buyer agents negotiate directly with AI seller agents, where sales and procurement transactions are executed in seconds, and where the friction points that have defined business-to-business (B2B) commerce for decades disappear. This is the potential of B2B agentic commerce—the use of AI agents to conduct business on behalf of enterprises across both the buyer and seller sides—and it is closer than most organizations realize.
Key takeaways
The timing is opportune. AI agents have matured dramatically over the past year, arriving just as enterprises are looking for new ways to navigate margin pressure, supply volatility, and labor constraints. Some B2B enterprises are already modernizing the core systems that agentic commerce will run on, creating a strategic window to build for an agent-ready future. Each of these pressures on its own would strain a business model. Together, they render "business as usual" increasingly untenable—and make the case for a faster, more agile, more autonomous operating model. The market also recognizes the imperative:
Leaders who their organization will be using agentic AI at least moderately within two years
Source: Deloitte’s 2026 State of AI in the Enterprise report
Estimated value of the AI agent market by the end of the decade
Source: Deloitte’s TMT Predictions 2026
In fact, Deloitte predicts AI agent market value could rise even higher to $45 billion if agents are strategically orchestrated and risks are appropriately mitigated.1
That realization surfaces a new set of defining questions for the future of B2B commerce: What is practical today? What happens as value chains become predominantly machine-to-machine? And how do enterprises navigate the shift from business as it was, to business as it will be?
The trajectory is clear: Near-term needs and long-term potential both point toward autonomous AI agents in commerce: agentic-driven negotiation at scale, closed working-capital loops, and direct agent-to-agent transactions across the enterprise. The question is no longer whether to move, but how quickly to operationalize agent-led business.
Before examining where agent-to-agent commerce is headed, it is worth grounding the conversation in where B2B enterprises stand today. Deloitte's 2026 B2B commerce research2, based on surveys of more than 1,000 US suppliers and buyers, reveals a market that is ambitious but unevenly prepared. Three patterns stand out:
Seventy-two percent of suppliers said their sales processes were mostly or highly automated. Only 47% of buyers agreed; in fact, buyers were six times more likely than suppliers to describe B2B processes as mostly manual. In other words, internal automation has not yet translated into the external buyer experience.
Buyers are adopting agentic AI faster than their suppliers. Nearly 40% of B2B buyers already use agentic AI in purchasing — evaluating products, configuring orders, reviewing contracts, and benchmarking prices. Supplier adoption is trailing but poised to grow, with 24% of suppliers using agents in the sales process and 67% reporting that they plan to in the future.
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The commercial stakes of these gaps are substantial. Suppliers estimate that, on average, 13% of sales bids are lost due to negative buyer experiences—that’s revenue left on the table because of friction that automation and agentic AI for sales are well-suited to resolve.
On the upside, positive buyer experiences drive an estimated 36% revenue uplift, and buyers spend nearly 30% more with suppliers that deliver them. Experience is a margin lever, not just a satisfaction metric.
The path toward a future where commerce is more autonomous relies on a singular capability: AI agents that can reason, act, and coordinate without continuous human direction.
As agents proliferate, the imperative is to move from thinking about them as stand-alone use cases (e.g., a sophisticated chatbot) to agentifying architecture and combining multiple agents to sell more directly and impactfully to customers. Agentic AI systems can set goals, perform multistep tasks, use tools and application programming interfaces (APIs), and coordinate with people or other agents—all within guardrails set by the enterprises that deploy them.
The shift is already beginning to show up across several B2B use cases, including:
This requires a transformational approach to enterprise strategy, technology investments, change management, risk mitigation, and numerous other business factors. It’s not just about adopting new technology; it’s a fundamental reimagination of B2B commerce and all the changes to strategy and operations that come with it.
Over the past year, agentic AI technology has matured from compelling one-off experiments into systems that can connect to tools and data, complete complex workflows, and orchestrate with other agents—and the pace is accelerating.
In their nascent forms, agents assist humans inside existing workflows—this is where most B2B enterprises sit today. In their fullest form, agents from different organizations transact directly with one another. Business-to-consumer (B2C) is proving this concept and paving the way for B2B to follow: Leading B2C enterprises are using agents to reach customers across channels, present offers dynamically, and reshape the shopping experience—with early signals that customer behavior is starting to shift.3
Today, most B2B businesses struggle to understand where they are in the agentic commerce trajectory, what the next stage requires, or what progress looks like. Let’s explore how the future of B2B commerce unfolds within the enterprise.
Achieving agent-to-agent interaction in commerce will take time due to the work and degree of change involved. There are likely to be stages of agentic maturity across the journey, with different sectors aspiring to different end states depending on readiness, risk tolerance, regulations, geography, and supply chain complexity. Recognizing these nuances, we can illustrate a common B2B agentic maturity pathway through an intelligent procurement use case, followed by the underlying sample architecture.
The stages below describe the progression of B2B agentic commerce via “workflow autonomy,” or how much of the buying and selling process agents own end to end. This is a counterpart to the consumer-journey progression outlined in Deloitte's Agentic commerce: Redefining retail economics thinking5, which maps the B2C path from assisted discovery through autonomous shopping to agent-to-agent commerce. Both progressions converge on the same end state: agentic systems from different organizations transacting directly with one another.
The right technical architecture is essential to the advancement described above. Agentic architecture integrates existing systems to enable autonomous commerce activities across a given enterprise and its ecosystem. For a closer look, explore our deep dive on the principles of agentic architecture and design.6
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How quickly organizations move from early use cases to enterprise-wide transformation depends in part on where the enterprise sits on the maturity spectrum and what they do next.
Where they are:
Agentic AI experiments are ticking up: 85% of companies anticipate customizing agents to automate aspects of the business, according to Deloitte’s most recent State of AI in the Enterprise report.7 While experimentation is valuable and important, it’s not an end in and of itself. Deloitte’s Tech Trends 20268 found only 11% of enterprises reported using agents in production, perhaps owing to the fact that 42% of organizations are still developing an agentic strategy and 35% have no strategy at all.
Where to next:
To reach the boldest future in agentic or autonomous commerce, businesses will need to contend with the complex task of industrializing multiagent systems. This goes beyond basic agent customization and compelling use cases. It entails a reimagination of workflows and responsibilities. It also includes activities such as ensuring clean master data, aligning a multicloud environment, developing APIs for task execution, securing data flows, attention to risk mitigation, and AI governance, and navigating the perennial questions around whether to buy or build agentic solutions.
The priority is to redesign processes with agents in mind, rather than layering agents onto existing workflows.
Because agentic commerce will touch or impact every part of the enterprise, the entire organization needs to be conditioned for the fully autonomous B2B future. With changes to brand strategy, investments, talent development, and more, the scale of transformation ahead requires significant, enterprise-wide work and change. The priority is to redesign processes with agents in mind, rather than layering agents onto existing workflows. Simply automating current processes risks carrying forward the manual constraints of the legacy model.
All technology presents risks that need to be mitigated, and agentic AI raises both familiar and new risks. Technology trust is essential, but regulatory compliance; customer privacy and security; and adapting roles, responsibilities, and incentives are just as important.
As with any AI solution, accuracy, reliability, and transparency are paramount. Agentic systems also run the risk of inaccuracies (or hallucinations) that propagate from machine to machine, degrading outputs. And because enterprise and operational data are the fuel that AI agents run on, data security is a priority in terms of designing agents to limit or remove data vulnerabilities.
In the B2B agent-to-agent commerce context, the risk landscape shifts as agent capabilities mature, presenting distinct challenges at different stages of adoption:
These risks and mitigation steps, however, should be weighed against a potentially greater risk: falling behind. According to our State of AI report,9 about 20% of companies report having a mature governance model for autonomous agents. These companies are laying the foundation for governance of agentic commerce and multiagent systems. What about the other 80%?
The potential value of B2B agentic commerce and the pace of industry adoption mean that "wait and see" strategies carry real competitive consequences. As agent-to-agent interactions become the norm, enterprises that delay transformation may find themselves competing with diminished efficiency, slower response times, and reduced market access.
In the future, agentic commerce will simply become commerce, and the question won't be whether to adapt but how quickly and thoughtfully organizations can do so while managing the risks inherent in any significant technology transition.
Some organizations are taking a more cautious view of technology investments, which is understandable. The degree of change required to reach the brightest future in agentic commerce can be daunting. When designing a B2B automation strategy, leaders and stakeholders can start by assessing and improving readiness across five broad categories.
Each readiness area commands its own competencies and questions, and it can be helpful to work with an adviser to define where your organization is today and which activities and investments are needed.
Agentic commerce is becoming a key agenda item for the board, and leaders across industries are moving forward. There is urgency to change among organizations of all levels of readiness. By beginning this journey today, enterprises can begin to capture the benefits of AI agents for sales and lead in the future of B2B.
Endnotes
1. Duncan Stewart, Jeff Loucks, and Paul Lee, TMT Predictions 2026, Deloitte, November 18, 2025.
2. Paul do Forno, Apurva Pangam, and Pooja Warudkar, “Accelerating sales growth through B2B digital commerce,” Deloitte, January 2026.
3. Vivek Pandya, “Adobe: AI-driven traffic surges across industries with retail experiencing biggest gains,” Adobe for Business Blog, January 12, 2026.
4. do Forno et al., “Accelerating sales growth through B2B digital commerce.”
5. Saurabh Vijayvergia, Brian McCarthy, and Roland Ehigiamusoe, “Agentic commerce: Redefining retail economics,” Deloitte, 2026.
6. Prakul Sharma et al., “The cognitive leap: How to reimagine work with AI agents,” Deloitte, December 2024.
7. Rowan et al., State of AI in the Enterprise 2026: The untapped edge.
8. Kelly Raskovich (ed.), Tech Trends 2026, Deloitte, December 10, 2025.
9. Rowan et al., State of AI in the Enterprise 2026: The untapped edge.