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Confidence under pressure: How life sciences leaders are recalibrating for the rest of 2026

Life sciences leaders say they’re focused on the economic and policy environment, while increasingly confident in their organizations’ ability to navigate it

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Based on new Deloitte research—including an April 2026 survey of 150 life sciences executives and an analysis of first-quarter earnings calls—life sciences leaders indicate a nuanced signal at midyear: Confidence is strengthening, but not necessarily because of any shifts in external conditions.

Just 9% of surveyed leaders said they were feeling more positive about the global economy than they were six months earlier. By contrast, 62% said they felt more positive or much more positive about their own company’s outlook compared with six months earlier.

As companies enter the second half of 2026, the focus tends to be on strengthening the fundamentals: productivity, commercial performance, investment discipline, partnerships, resilience, and artificial intelligence deployment. While the external environment may remain uncertain, leaders appear increasingly confident in their ability to perform within it.

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